Chicken And Biscuit Casserole

Highlighted under: Everyday Collection

I absolutely love making Chicken and Biscuit Casserole, as it brings together the comforting flavors of home-cooked meals and the convenience of one-dish cooking. The savory chicken paired with creamy sauce and fluffy biscuits creates a delightful experience for both my family and friends. It's the perfect dish for gatherings or even a cozy night in. The best part? It comes together in no time, making it an easy yet hearty option that never disappoints.

Lottie Pennington

Created by

Lottie Pennington

Last updated on 2026-01-24T13:09:35.106Z

When I first tried my hand at creating a Chicken and Biscuit Casserole, I was a bit intimidated, but it quickly became a favorite. I remember experimenting with different spices and finding the perfect blend that complements the chicken and biscuit layer beautifully. It was essential to get the sauce just right; not too runny, but creamy enough to soak into the biscuits.

One detail that made a significant difference was preparing the chicken with a little garlic powder and thyme before adding it to the casserole. This simple step brought an incredible depth of flavor that elevated the dish from ordinary to extraordinary. I often find myself craving this dish, especially on chilly evenings!

Why You Will Love This Recipe

  • A comforting combination of tender chicken and flaky biscuits
  • Rich, creamy sauce that brings the entire dish together
  • Perfect for any family dinner or special occasion

The Role of Chicken and Vegetables

In this Chicken and Biscuit Casserole, the shredded chicken is the star that provides protein and a rich flavor base. Using leftover roast chicken or rotisserie chicken not only saves time but also infuses the dish with a depth of flavor that enhances the creamy sauce. If you're in a pinch, even canned chicken can work, but fresh is always best for texture and taste.

The frozen mixed vegetables add color and nutrition, making this a balanced dish in one serving. Peas, carrots, and corn pair wonderfully, providing a slight sweetness that complements the savory chicken. Feel free to swap in your favorites, such as green beans or broccoli; just make sure they are cooked slightly before adding to ensure even heating during baking.

Biscuit Techniques for Fluffiness

The choice of biscuits can greatly influence the final texture of your casserole. For truly fluffy biscuits, I recommend avoiding the flaky layers in favor of a classic biscuit dough that rises beautifully in the oven. When cutting the biscuits into quarters, try not to compress them too much; gentle handling promotes a light texture that will bake up nicely on top of the casserole. An alternative could be homemade biscuits using your favorite baking powder recipe for a personal touch.

Also, consider adding a bit of melted butter brushed on top of the biscuits before baking for an extra golden color and a touch of flavor. This technique not only enhances the visual appeal but also creates a slightly crisp surface contrast against the creamy filling below.

Serving and Storage Suggestions

Once the casserole is baked to golden perfection, allow it to cool for about 10 minutes before serving. This resting time lets the filling set slightly, making it easier to portion. Serve it alongside a simple side salad to balance the richness, or even add a dollop of hot sauce or a sprinkle of freshly chopped herbs like parsley for a pop of color and flavor.

If you have leftovers, store them in an airtight container in the refrigerator for up to three days. To reheat, cover with foil and bake at 350°F (175°C) for about 20-25 minutes, or until heated through. This casserole also freezes well. Simply layer the filling and unbaked biscuits in a freezer-safe dish, and it’ll keep for up to three months. Bake straight from frozen, adding an extra 10-15 minutes to the cooking time until bubbly and golden.

Ingredients

Gather all the ingredients before starting for an easy cooking experience.

Ingredients

  • 2 cups cooked chicken, shredded
  • 1 can (10.5 oz) cream of chicken soup
  • 1 cup milk
  • 1 cup frozen mixed vegetables (peas, carrots, corn)
  • 1 teaspoon garlic powder
  • 1 teaspoon thyme
  • 1 package (8 oz) refrigerated biscuits
  • Salt and pepper to taste
  • 1/2 cup shredded cheddar cheese (optional)

Make sure to have everything measured out for better efficiency while cooking!

Instructions

Follow these steps to create your delicious casserole.

Preheat the Oven

Preheat your oven to 375°F (190°C).

Prepare the Filling

In a large bowl, combine shredded chicken, cream of chicken soup, milk, frozen mixed vegetables, garlic powder, thyme, salt, and pepper. Mix well.

Transfer to Baking Dish

Pour the chicken mixture into a greased 9x13 inch baking dish, spreading it evenly.

Add Biscuits

Cut the refrigerated biscuits into quarters and evenly distribute them over the top of the chicken mixture.

Bake

Bake in the preheated oven for 30 minutes, or until the biscuits are golden brown.

Serve

Let the casserole cool for a few minutes before serving. Optionally, sprinkle with cheddar cheese before serving for an extra cheesy touch.

Enjoy your hearty Chicken and Biscuit Casserole!

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Pro Tips

  • For extra flavor, consider adding some sautéed onions or mushrooms to the chicken mixture before baking.

Customizable Variations

One of the best features of this Chicken and Biscuit Casserole is its versatility. You can easily cater it to fit different dietary preferences or what you have on hand. For a creamy twist, consider adding a bit of sour cream or cream cheese to the sauce mixture, creating a richer mouthfeel that elevates the dish even further. If you're feeling adventurous, you can experiment with flavors, such as adding ranch seasoning mix or a splash of hot sauce to kick up the heat.

For a lighter version, swap the cream of chicken soup with a homemade sauce made from sautéed onions, garlic, and chicken broth thickened with a bit of flour or cornstarch. This approach improves the overall flavor profile and cuts down on preservatives.

Troubleshooting Tips

When baking the casserole, one common issue is undercooked biscuits, which can lead to a soggy texture if not properly baked. Always ensure the oven is preheated thoroughly and consider checking the biscuits a few minutes before the full baking time is up if they seem to be browning slowly. If they haven’t puffed up by the end of the cooking time, you can rotate the casserole for even heat distribution.

If you notice the top of the casserole browning too quickly before the filling is bubbling, cover the dish lightly with aluminum foil. This will prevent burning while allowing the dish to finish cooking through. A fully bubbly filling is a sign that your dinner is ready to be enjoyed!

Questions About Recipes

→ Can I use leftover rotisserie chicken?

Absolutely! Leftover rotisserie chicken works great for this recipe.

→ Is it possible to make it ahead of time?

Yes, you can prepare everything and store it in the refrigerator before baking.

→ Can I substitute the cream of chicken soup?

Yes, you can use a homemade version or substitute it with cream of mushroom soup.

→ What can I serve with this casserole?

This casserole is filling on its own, but a fresh salad would make a great side.

Chicken And Biscuit Casserole

I absolutely love making Chicken and Biscuit Casserole, as it brings together the comforting flavors of home-cooked meals and the convenience of one-dish cooking. The savory chicken paired with creamy sauce and fluffy biscuits creates a delightful experience for both my family and friends. It's the perfect dish for gatherings or even a cozy night in. The best part? It comes together in no time, making it an easy yet hearty option that never disappoints.

Prep Time20 minutes
Cooking Duration30 minutes
Overall Time50 minutes

Created by: Lottie Pennington

Recipe Type: Everyday Collection

Skill Level: Intermediate

Final Quantity: 6 servings

What You'll Need

Ingredients

  1. 2 cups cooked chicken, shredded
  2. 1 can (10.5 oz) cream of chicken soup
  3. 1 cup milk
  4. 1 cup frozen mixed vegetables (peas, carrots, corn)
  5. 1 teaspoon garlic powder
  6. 1 teaspoon thyme
  7. 1 package (8 oz) refrigerated biscuits
  8. Salt and pepper to taste
  9. 1/2 cup shredded cheddar cheese (optional)

How-To Steps

Step 01

Preheat your oven to 375°F (190°C).

Step 02

In a large bowl, combine shredded chicken, cream of chicken soup, milk, frozen mixed vegetables, garlic powder, thyme, salt, and pepper. Mix well.

Step 03

Pour the chicken mixture into a greased 9x13 inch baking dish, spreading it evenly.

Step 04

Cut the refrigerated biscuits into quarters and evenly distribute them over the top of the chicken mixture.

Step 05

Bake in the preheated oven for 30 minutes, or until the biscuits are golden brown.

Step 06

Let the casserole cool for a few minutes before serving. Optionally, sprinkle with cheddar cheese before serving for an extra cheesy touch.

Extra Tips

  1. For extra flavor, consider adding some sautéed onions or mushrooms to the chicken mixture before baking.

Nutritional Breakdown (Per Serving)

  • Calories: 480 kcal
  • Total Fat: 23g
  • Saturated Fat: 10g
  • Cholesterol: 75mg
  • Sodium: 920mg
  • Total Carbohydrates: 43g
  • Dietary Fiber: 2g
  • Sugars: 3g
  • Protein: 22g